Wednesday, February 21, 2018

Tau accumulations in the brains of woodpeckers


Dr. Peter Cummings makes another appearance on the blog, this time as senior author on a paper entitled: Tau Accumulations in the Brains of Woodpeckers. Eight of ten woodpeckers examined showed cerebral tau accumulations, whereas no control brains (red-winged blackbirds) were positive.This is significant in that there has been some research interest in developing football helmets based on the protective design that has evolved to protect the brains of woodpeckers.But maybe the relatively short life of the woodpecker (average less than 10 years) precludes the need to this protective adaptation. Thanks to Dr. Mark Cohen for alerting me to this study.

Tuesday, February 20, 2018

AANP meeting abstract submission deadline extended

American Association of Neuropathologists annual meeting abstract submission deadline has been EXTENDED to March 6, 2018 at 11:59 EST.

Wednesday, February 14, 2018

Las Vegas gunman had unusually high burden of corpora amylacea, but no other significant findings, at autopsy

The New York Times reports that brain autopsy results on Las Vegas gunman Stephen Paddock show that he "had not had a stroke, brain tumor or a number of other neurological disorders that might have helped explain his actions". 

Paddock, 64-years-old, did have an unusually high burden of corpora amylacea, the significance of which is not known.

In the article, Stanford neuropathologist Hannes Vogel commented on the corpora amylacea as follows: “Most people would have them at that age, but not in that profusion,” Dr. Vogel said. “It’s a striking exaggeration of an age-related finding.”

I put up a post a few months ago about Dr. Vogel receiving the brain for examination.

Friday, February 9, 2018

Registration and Abstract Submission for 19th International Congress of Neuropathology (ICN2018 Tokyo) now open



The organizing committees for the 19th International Congress of Neuropathology (ICN2018 Tokyo) have announced that registration and abstract submission for the meeting have officially opened as of Wednesday, February 7, 2018.  ICN2018 Tokyo will take place September 23-27, 2018.  For more information, click here.

Wednesday, February 7, 2018

Meningioma involved by mantle cell lymphoma

70-year-old female with a right frontal lobe mass. Before the meningioma presented itself, the patient already carried the diagnosis of mantle cell lymphoma on peripheral blood analysis.



meningioma

lymphoma

Tuesday, February 6, 2018

Best Post of December 2017: A message from American Association of Neuropathologists President Elizabeth Cochran

The next in our "Best of the Month" series is form Monday, December 18, 2017. Good to be reminded of the upcoming meeting:


Louisville, KY
AANP members are already prepping for the 94th Annual Meeting, to be held in Louisville, KY, June 7-10, 2018.  Annual Meeting registration and the abstract submission site have launched, and the call for DSS cases has been sent. We are looking forward to seeing you in Kentucky!

Monday, February 5, 2018

TBI Linked to Increased Dementia Risk Over Several Years

The following is adapted from a recent post on practiceupdate.com:
Traumatic brain injury (TBI) is associated with persistently increased risk of dementia, according to a study published online Jan. 30 in PLOS Medicine.

Anna Nordström, M.D., Ph.D., and Peter Nordström, M.D., Ph.D., both from Umeå University in Sweden, tracked dementia and TBI diagnoses among all 3,329,360 individuals in Sweden

The correlation was strongest in the first year after TBI (odds ratio, 3.52) and persisted at >30 years (odds ratio, 1.25). A weaker association with dementia was seen for single mild TBI versus more severe TBI or multiple TBIs (odds ratios, 1.63 versus 2.06 and 2.81, respectively). Among sibling pairs with discordant TBI status, TBI correlated with increased risk of dementia diagnosis (odds ratio, 1.89).

"The risk of dementia diagnosis decreased over time after TBI, but it was still evident >30 years after the trauma," the authors write.